NOAEL Studies Cosmetic Ingredient

PEG-3 2,2'-DI-P-PHENYLENEDIAMINE NOAEL Studies

CAS: 144644-13-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCNFP Opinion 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =10 mg/kg bw - dermal Sub-chronic repeated dose toxicity p.6
SCCNFP Opinion NOAEL =45 mg/kg bw rat - - dermal absorption p.11
SCCNFP Opinion NOAEL =200 mg/kg bw rat - - dermal absorption p.11
Regulatory source 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source dermal absorption 45 mg/kg bw rat - - dermal absorption p.11
Regulatory source dermal absorption 200 mg/kg bw rat - - dermal absorption p.11
Regulatory source irritation 10 mg/kg bw rat oral 13 weeks irritation p.15
Regulatory source irritation 200 mg/kg bw rat oral 13 weeks irritation p.15
Regulatory source repeated dose toxicity 10 mg/kg bw - dermal Sub-chronic repeated dose toxicity p.6