Good Cosmetic Ingredient NOAEL Data

PEG-3 COCAMINE

Also known as: PEG-4 cocamine, Ethoxylated cocoamines, UNII-28053HD34J, UNII-2F9J4Q575K, UNII-8L6LB12TSJ (+4 more)

PEG-3 COCAMINE (CAS 61791-14-8) is a cosmetic cosmetic ingredient functioning as Surfactant - Emulsifying. Reported NOAEL =5 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 61791-14-8 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant - Emulsifying
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status allowed
US Notes Allowed

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Toxicological Studies

10 study endpoints found for PEG-3 COCAMINE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =5 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =5 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =5 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =5 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =12 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex
NOAEL =12 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex
NOAEL =12 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex
NOAEL =12 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex
NOAEL =13 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex
NOAEL =13 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Cleaning agent Dispersing agent Emulsifier Surface modifier Surfactant (surface active agent) Thickening agent Wetting agent (non-aqueous)
Regulatory List Membership (1)
FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for PEG-3 COCAMINE.

Regulatory Flags

cosing-sourced eu-permitted surfactant needs-enrichment

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to PEG-3 COCAMINE by CAS number or substance name.

Studies
48
Lowest NOAEL
5 mg/kg/d
Highest NOAEL
134 mg/kg/d
CIR_vision_codex

Known Synonyms

PEG-4 cocamine Ethoxylated cocoamines UNII-28053HD34J UNII-2F9J4Q575K UNII-8L6LB12TSJ UNII-KTM00873VC UNII-PMT39AFQ4Z UNII-Z99UKQ29D9 UNII-ZA36V5XS8F

Chemical Function

Surfactant (surface active agent) Emulsifier Cleaning agent

Regulatory Lists

inert_ingredient; non_food_use; Pesticides Indirect additives food contact (10/2018) Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff

Australian Status

AICIS status: listed

Frequently Asked Questions

Is PEG-3 COCAMINE safe in cosmetics?

PEG-3 COCAMINE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed. 10 toxicological study endpoint(s) are available in our database.

Is PEG-3 COCAMINE allowed in the EU?

PEG-3 COCAMINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG-3 COCAMINE do in cosmetics?

PEG-3 COCAMINE functions as: Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 61791-14-8.

What is the NOAEL for PEG-3 COCAMINE?

The NOAEL (No Observed Adverse Effect Level) for PEG-3 COCAMINE is =5 mg/kg/d based on a developmental toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.

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