Moderate Cosmetic Ingredient

PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone

INCI: PEG/PPG-24/24 METHYL ETHER GLYCIDOXY DIMETHICONE

CAS Number
68937-54-2 (generic; glycidoxy-modified variant)
Function
Surfactant — Emulsifying; Film Former
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA; limited individual data — read-across from CIR 2014 polyoxyalkylene siloxane group applies with caveats

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Glycidoxy (epoxide) group presents potential genotoxic and sensitizing concern from residual unreacted epoxide; 1,4-dioxane and ethylene oxide residuals; D4/D5 traces possible; supplier certificate of analysis confirming residual epoxide levels required.

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Concern Level: High

Regulatory Flags

potential-allergen peg-ingredient

Frequently Asked Questions

Is PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone safe in cosmetics?

Glycidoxy (epoxide) group presents potential genotoxic and sensitizing concern from residual unreacted epoxide; 1,4-dioxane and ethylene oxide residuals; D4/D5 traces possible; supplier certificate of analysis confirming residual epoxide levels required. The EU classifies PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone as "permitted". Safety rating: MODERATE.

Is PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone allowed in the EU?

PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone do in cosmetics?

PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone functions as: Surfactant — Emulsifying; Film Former. It is classified as a cosmetic ingredient in our database. CAS number: 68937-54-2 (generic; glycidoxy-modified variant).

What is the Margin of Safety for PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check PEG/PPG-24/24 Methyl Ether Glycidoxy Dimethicone compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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