PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin

INCI: PEG/PPG/POLYBUTYLENE GLYCOL-8/5/3 GLYCERIN

CAS Number
Not publicly assigned (proprietary)
Function
Humectant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA: not restricted; no specific CIR monograph โ€” read-across from PEG/PPG class

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

MW <1,000 Da permits some dermal penetration; warrants ingredient-specific NOAEL for robust MoS calculation. Standard ethoxylation residuals apply.

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Concern Level: Low

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin safe in cosmetics?

MW <1,000 Da permits some dermal penetration; warrants ingredient-specific NOAEL for robust MoS calculation. Standard ethoxylation residuals apply. The EU classifies PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin as "permitted". Safety rating: GOOD.

Is PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin allowed in the EU?

PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin do in cosmetics?

PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin functions as: Humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (proprietary).

What is the Margin of Safety for PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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