PEI-1000

CAS Number
9002-98-6
Function
Binder; Chelating agent; Dispersing agent; Viscosity modifier
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes FDA: not specifically restricted; limited CIR data at this MW grade

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High cationic charge density presents significant irritation and cytotoxicity concern at moderate concentrations; membrane disruption and cytotoxicity are proportional to molecular weight; in vitro irritation testing and strict concentration limits required for safety justification.

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Concern Level: High

Frequently Asked Questions

Is PEI-1000 safe in cosmetics?

High cationic charge density presents significant irritation and cytotoxicity concern at moderate concentrations; membrane disruption and cytotoxicity are proportional to molecular weight; in vitro irritation testing and strict concentration limits required for safety justification. The EU classifies PEI-1000 as "permitted". Safety rating: MODERATE.

Is PEI-1000 allowed in the EU?

PEI-1000 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEI-1000 do in cosmetics?

PEI-1000 functions as: Binder; Chelating agent; Dispersing agent; Viscosity modifier. It is classified as a cosmetic ingredient in our database. CAS number: 9002-98-6.

What is the Margin of Safety for PEI-1000?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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