PEI-7

CAS Number
9002-98-6 (polyethylenimine)
Function
Film forming, viscosity controlling
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed by FDA; no dedicated CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Lowest MW PEI in this set with significantly higher cytotoxicity and dermal penetration potential versus higher-MW grades; in vitro cytotoxicity of low-MW PEI is well-established in pharmaceutical literature.

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Concern Level: High

Frequently Asked Questions

Is PEI-7 safe in cosmetics?

Lowest MW PEI in this set with significantly higher cytotoxicity and dermal penetration potential versus higher-MW grades; in vitro cytotoxicity of low-MW PEI is well-established in pharmaceutical literature. The EU classifies PEI-7 as "restricted". Safety rating: MODERATE.

Is PEI-7 allowed in the EU?

PEI-7 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEI-7 do in cosmetics?

PEI-7 functions as: Film forming, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 9002-98-6 (polyethylenimine).

What is the Margin of Safety for PEI-7?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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