Moderate Cosmetic Ingredient NOAEL Data

Pelargonic Acid

INCI: PELARGONIC ACID

CAS Number
112-05-0
Function
Skin conditioning agent, cleansing agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR reviewed โ€” safe as used (2011); FDA GRAS as a food flavoring; also EPA-registered herbicide

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Pelargonic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1500 mg/kg bw/day oral rat Developmental COSMOS_DB
dose_tested 1500 mg/kg bw/day oral rat Developmental COSMOS_DB

Expert Verdict

Pelargonic acid is a significant skin and eye irritant at undiluted concentrations; CIR conclusion applies to esters as used, with no phototoxicity concern demonstrated.

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Concern Level: Moderate

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Pelargonic Acid safe in cosmetics?

Pelargonic acid is a significant skin and eye irritant at undiluted concentrations; CIR conclusion applies to esters as used, with no phototoxicity concern demonstrated. The EU classifies Pelargonic Acid as "restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Pelargonic Acid allowed in the EU?

Pelargonic Acid EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pelargonic Acid do in cosmetics?

Pelargonic Acid functions as: Skin conditioning agent, cleansing agent. It is classified as a cosmetic ingredient in our database. CAS number: 112-05-0.

What is the Margin of Safety for Pelargonic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Pelargonic Acid?

The NOAEL (No Observed Adverse Effect Level) for Pelargonic Acid is 1500 mg/kg bw/day based on a Developmental study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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