Pentaerythrityl Tetra C5-9 Acid Esters
INCI: PENTAERYTHRITYL TETRA C5-9 ACID ESTERS
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Pentaerythrityl Tetra C5-9 Acid Esters. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 12500 ppm | oral | rat | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 12500 ppm | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1613 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1613 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Minimal epidermal hyperplasia and chronic dermal inflammation at sustained high-dose dermal exposure. Inhalation considerations for spray formats.
Frequently Asked Questions
Is Pentaerythrityl Tetra C5-9 Acid Esters safe in cosmetics?
Minimal epidermal hyperplasia and chronic dermal inflammation at sustained high-dose dermal exposure. Inhalation considerations for spray formats. The EU classifies Pentaerythrityl Tetra C5-9 Acid Esters as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Pentaerythrityl Tetra C5-9 Acid Esters allowed in the EU?
Pentaerythrityl Tetra C5-9 Acid Esters EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pentaerythrityl Tetra C5-9 Acid Esters do in cosmetics?
Pentaerythrityl Tetra C5-9 Acid Esters functions as: Hair-conditioning agent, plasticizer, skin-conditioning agent—miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: 67762-53-2.
What is the Margin of Safety for Pentaerythrityl Tetra C5-9 Acid Esters?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Pentaerythrityl Tetra C5-9 Acid Esters?
The NOAEL (No Observed Adverse Effect Level) for Pentaerythrityl Tetra C5-9 Acid Esters is 12500 ppm based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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