Pentaerythrityl Tetraacrylate

INCI: PENTAERYTHRITYL TETRAACRYLATE

CAS Number
4986-89-4
Function
Crosslinking agent and film former used primarily in UV-curable nail systems and industrial coatings
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; no CIR safety assessment for the monomer

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Unreacted acrylate monomer is a potent skin sensitizer and irritant. Acceptable only in UV-cured systems such as gel nails where full polymerization occurs and residual monomer is minimized. Not suitable for leave-on skin products. Occupational exposure limits apply. Requires quantified residual monomer specifications of less than 0.1% free monomer post-cure.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Pentaerythrityl Tetraacrylate safe in cosmetics?

Unreacted acrylate monomer is a potent skin sensitizer and irritant. Acceptable only in UV-cured systems such as gel nails where full polymerization occurs and residual monomer is minimized. Not suitable for leave-on skin products. Occupational exposure limits apply. Requires quantified residual monomer specifications of less than 0.1% free monomer post-cure. The EU classifies Pentaerythrityl Tetraacrylate as "permitted". Safety rating: POOR.

Is Pentaerythrityl Tetraacrylate allowed in the EU?

Pentaerythrityl Tetraacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pentaerythrityl Tetraacrylate do in cosmetics?

Pentaerythrityl Tetraacrylate functions as: Crosslinking agent and film former used primarily in UV-curable nail systems and industrial coatings. It is classified as a cosmetic ingredient in our database. CAS number: 4986-89-4.

What is the Margin of Safety for Pentaerythrityl Tetraacrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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