Poor Cosmetic Ingredient

Perfluorohexyl Ethylphosphonic Acid

INCI: PERFLUOROHEXYL ETHYLPHOSPHONIC ACID

CAS Number
252237-40-4
Function
Surfactant – cleansing
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status restricted
US Notes Not specifically restricted by FDA; not singled out in MoCRA PFAS report; subject to CA AB 2771 (intentionally added PFAS banned in cosmetics)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS with environmental persistence and irreversible BChE inhibition; developmental toxicity observed in zebrafish; potential PFHxA precursor; restricted under California AB 2771.

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Concern Level: High

Frequently Asked Questions

Is Perfluorohexyl Ethylphosphonic Acid safe in cosmetics?

PFAS with environmental persistence and irreversible BChE inhibition; developmental toxicity observed in zebrafish; potential PFHxA precursor; restricted under California AB 2771. The EU classifies Perfluorohexyl Ethylphosphonic Acid as "prohibited". Safety rating: POOR.

Is Perfluorohexyl Ethylphosphonic Acid allowed in the EU?

Perfluorohexyl Ethylphosphonic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Perfluorohexyl Ethylphosphonic Acid do in cosmetics?

Perfluorohexyl Ethylphosphonic Acid functions as: Surfactant – cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 252237-40-4.

What is the Margin of Safety for Perfluorohexyl Ethylphosphonic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Perfluorohexyl Ethylphosphonic Acid compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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