Regulatory Status
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Safety Data
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Expert Verdict
CRITICAL: Root extract carries same pyrrolizidine alkaloid (PA) risk as leaf extract with potentially different PA profile; CO2 supercritical extraction can reduce PAs but requires analytical verification; petasin and isopetasin are non-toxic but co-extracted PAs present significant hepatotoxicity concern.
Regulatory Flags
Frequently Asked Questions
Is Petasites Hybridus Root Extract safe in cosmetics?
CRITICAL: Root extract carries same pyrrolizidine alkaloid (PA) risk as leaf extract with potentially different PA profile; CO2 supercritical extraction can reduce PAs but requires analytical verification; petasin and isopetasin are non-toxic but co-extracted PAs present significant hepatotoxicity concern. The EU classifies Petasites Hybridus Root Extract as "permitted". Safety rating: POOR.
Is Petasites Hybridus Root Extract allowed in the EU?
Petasites Hybridus Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Petasites Hybridus Root Extract do in cosmetics?
Petasites Hybridus Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90082-63-6.
What is the Margin of Safety for Petasites Hybridus Root Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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