Petasites Japonicus Leaf/Stem Extract

INCI: PETASITES JAPONICUS LEAF/STEM EXTRACT

CAS Number
91845-41-9
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA monograph; permitted as cosmetic botanical

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Leaf/stem combination may carry higher pyrrolizidine alkaloid load than leaf alone due to stem vascular tissue concentrating alkaloids; requires LC-MS/MS pyrrolizidine alkaloid panel verification per Ph. Eur. 2.8.26

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Petasites Japonicus Leaf/Stem Extract safe in cosmetics?

Leaf/stem combination may carry higher pyrrolizidine alkaloid load than leaf alone due to stem vascular tissue concentrating alkaloids; requires LC-MS/MS pyrrolizidine alkaloid panel verification per Ph. Eur. 2.8.26 The EU classifies Petasites Japonicus Leaf/Stem Extract as "permitted". Safety rating: POOR.

Is Petasites Japonicus Leaf/Stem Extract allowed in the EU?

Petasites Japonicus Leaf/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Petasites Japonicus Leaf/Stem Extract do in cosmetics?

Petasites Japonicus Leaf/Stem Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 91845-41-9.

What is the Margin of Safety for Petasites Japonicus Leaf/Stem Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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