Petasites Japonicus Root Extract

INCI: PETASITES JAPONICUS ROOT EXTRACT

CAS Number
91845-41-9
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA; no CIR final report. PA-free preparations (patented processes) exist

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Root tissues are known PA reservoirs. Petasin/isopetasin are active sesquiterpenes but co-occur with toxic PAs. Only PA-free standardized extracts are acceptable

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Petasites Japonicus Root Extract safe in cosmetics?

Root tissues are known PA reservoirs. Petasin/isopetasin are active sesquiterpenes but co-occur with toxic PAs. Only PA-free standardized extracts are acceptable The EU classifies Petasites Japonicus Root Extract as "permitted". Safety rating: POOR.

Is Petasites Japonicus Root Extract allowed in the EU?

Petasites Japonicus Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Petasites Japonicus Root Extract do in cosmetics?

Petasites Japonicus Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 91845-41-9.

What is the Margin of Safety for Petasites Japonicus Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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