Phenylisopropyl Dimethicone

INCI: PHENYLISOPROPYL DIMETHICONE

CAS Number
Not uniquely assigned (silicone copolymer; CosIng Ref 59283) [^1_20]
Function
Conditioning agent
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA โ€” no restriction; silicones broadly accepted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Silicone copolymer with excellent safety profile. Ensure D4/D5/D6 cyclomethicone residuals comply with EU Annex II limits (D4 banned; D5/D6 restricted in wash-off at concentrations >0.1%).

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Concern Level: Low

Frequently Asked Questions

Is Phenylisopropyl Dimethicone safe in cosmetics?

Silicone copolymer with excellent safety profile. Ensure D4/D5/D6 cyclomethicone residuals comply with EU Annex II limits (D4 banned; D5/D6 restricted in wash-off at concentrations >0.1%). The EU classifies Phenylisopropyl Dimethicone as "permitted". Safety rating: EXCELLENT.

Is Phenylisopropyl Dimethicone allowed in the EU?

Phenylisopropyl Dimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phenylisopropyl Dimethicone do in cosmetics?

Phenylisopropyl Dimethicone functions as: Conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (silicone copolymer; CosIng Ref 59283) [^1_20].

What is the Margin of Safety for Phenylisopropyl Dimethicone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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