Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Phosphate Buffered Saline is a non-irritating solvent and buffering agent primarily used as a delivery vehicle for active ingredients, with CIR confirmation of safety at current usage levels.
Frequently Asked Questions
Is Phosphate Buffered Saline safe in cosmetics?
Phosphate Buffered Saline is a non-irritating solvent and buffering agent primarily used as a delivery vehicle for active ingredients, with CIR confirmation of safety at current usage levels. The EU classifies Phosphate Buffered Saline as "permitted". Safety rating: EXCELLENT.
Is Phosphate Buffered Saline allowed in the EU?
Phosphate Buffered Saline EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phosphate Buffered Saline do in cosmetics?
Phosphate Buffered Saline functions as: Solvent, buffering agent. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (mixture: NaCl, KCl, Na₂HPO₄, KH₂PO₄).
What is the Margin of Safety for Phosphate Buffered Saline?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Phosphate Buffered Saline compliance across multiple jurisdictions:
Related Ingredients
Is Phosphate Buffered Saline in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Phosphate Buffered Saline in your formulation.