NOAEL Studies
Cosmetic Ingredient
Phthalic Anhydride NOAEL Studies
INCI: PHTHALIC ANHYDRIDE
CAS: 85-44-9
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
Regulatory source 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| Regulatory source | LOAEL | =1562 | mg/kg/day | - | oral | chronic | IRIS chronic oral RfD system PoD | row_hash=f3cbb66737852492; file=iris_rfd_systems.csv; kind=point_of_departure; raw_column=point_of_departure; raw_value=LOAEL : 1.562e3 mg/kg-day; system=Urinary, Respiratory; basis=Lung and kidney histopathology; point_of_departure=LOAEL : 1.562e3 mg/kg-day; composite_uf=1000; confidence=Medium; dtxsid=DTXSID2021159; detail_url=https://iris.epa.gov/ChemicalLanding/&substance_nmbr=308; rfd_last_updated=09/07/1988; rfd_pdf_url=https://iris.epa.gov/static/pdfs/0308_summary.pdf |
| Regulatory source | RfD | =2 | mg/kg/day | - | oral | chronic | IRIS chronic oral RfD system | row_hash=02e65e9ebd2a16da; file=iris_rfd_systems.csv; kind=reference_value; raw_column=rfd_mg_per_kg_day; raw_value=2; system=Urinary, Respiratory; basis=Lung and kidney histopathology; point_of_departure=LOAEL : 1.562e3 mg/kg-day; composite_uf=1000; confidence=Medium; dtxsid=DTXSID2021159; detail_url=https://iris.epa.gov/ChemicalLanding/&substance_nmbr=308; rfd_last_updated=09/07/1988; rfd_pdf_url=https://iris.epa.gov/static/pdfs/0308_summary.pdf |
NTP ICE acute inhalation 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP ICE acute inhalation | LC50 | >0.21 | mg/L | - | Inhalation | Duration=1 hr | In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity | sheet=Data; excel_row=1369; Record_ID=acute_inhalation_3044; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=0.21; Response_Unit=mg/L; Reference=ChemIDplus; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
NTP ICE acute oral 9 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP ICE acute oral | LD50 | >800 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_10942; row=3904; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | >1500 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_10944; row=3898; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | =1530 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_10946; row=3897; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | <1600 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_10948; row=3896; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | <2000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_10950; row=3899; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | >2500 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_10952; row=3900; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | =4020 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_10954; row=3901; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | =4500 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | JRC AcutoxBase (undated); record_id=acute_oral_10956; row=3902; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
| NTP ICE acute oral | LD50 | <5000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_10958; row=3903; data_type=In Vivo; mixture=Chemical; chemical_name=Phthalic anhydride; preferred_name=Phthalic anhydride; dtxsid=DTXSID2021159; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID2021159; source_file=acute_oral.xlsx |
NTP ICE cancer 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP ICE cancer | Top dose | 15000 | ppm | Rat | - | - | In Vivo; NTP Carcinogenicity | sheet=Data; excel_row=2594; Record_ID=cancer_4497; Data_Type=In Vivo; Formulation_Name=Phthalic anhydride; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=NTP Carcinogenicity; Endpoint=Top dose; Response=15000; Response_Unit=ppm; Species=Rat; Strain=F344/N; Sex=Female; Reference=TR-159; URL=https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr159/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE cancer | Top dose | 24038 | ppm | Mouse | - | - | In Vivo; NTP Carcinogenicity | sheet=Data; excel_row=2601; Record_ID=cancer_4494; Data_Type=In Vivo; Formulation_Name=Phthalic anhydride; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=NTP Carcinogenicity; Endpoint=Top dose; Response=24038; Response_Unit=ppm; Species=Mouse; Strain=B6C3F1; Sex=Female; Reference=TR-159; URL=https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr159/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE cancer | Top dose | 32692 | ppm | Mouse | - | - | In Vivo; NTP Carcinogenicity | sheet=Data; excel_row=2598; Record_ID=cancer_4493; Data_Type=In Vivo; Formulation_Name=Phthalic anhydride; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=NTP Carcinogenicity; Endpoint=Top dose; Response=32692; Response_Unit=ppm; Species=Mouse; Strain=B6C3F1; Sex=Male; Reference=TR-159; URL=https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr159/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
NTP ICE skin sensitization 21 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP ICE skin sensitization | CD86, EC150 | 160 | ug/mL | - | Dermal | - | In Vitro; Urbisch_SkinSensitization2020; U-SENS | sheet=Data_invitro; excel_row=8333; Record_ID=skin_sensitization_invitro_2310; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=1080.227118; Reported_Response_Unit=uM; Conversion_Factor_Value=148.117; Conversion_Factor_Source=EPA Dashboard; Converted_Response=160; Converted_Response_Unit=ug/mL; Response=160; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | CV75 | 400 | ug/mL | - | Dermal | - | In Vitro; hCLAT2015; h-CLAT | sheet=Data_invitro; excel_row=3157; Record_ID=skin_sensitization_invitro_723; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=h-CLAT; Endpoint=CV75; Reported_Response=400; Reported_Response_Unit=ug/mL; Response=400; Response_Unit=ug/mL; Reference=Ashikaga et al. 2010; 20822320; 10.1177/026119291003800403|Nukada et al. 2012; 22796097; 10.1016/j.tiv.2012.07.001|Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | CV75 | 416.7 | ug/mL | - | Dermal | - | In Vitro; hCLAT2015; h-CLAT | sheet=Data_invitro; excel_row=3114; Record_ID=skin_sensitization_invitro_725; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=h-CLAT; Endpoint=CV75; Reported_Response=416.7; Reported_Response_Unit=ug/mL; Response=416.7; Response_Unit=ug/mL; Reference=Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Cys | -7 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1006; Record_ID=skin_sensitization_invitro_275; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=-7; Reported_Response_Unit=%; Response=-7; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Cys | 0 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1002; Record_ID=skin_sensitization_invitro_274; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=0; Reported_Response_Unit=%; Response=0; Response_Unit=%; Reference=Jaworska 2011; 23670904; 10.1002/jat.2869; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Cys | 1.9 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=998; Record_ID=skin_sensitization_invitro_273; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=1.9; Reported_Response_Unit=%; Response=1.9; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Cys | 16.7 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=994; Record_ID=skin_sensitization_invitro_272; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=16.7; Reported_Response_Unit=%; Response=16.7; Response_Unit=%; Reference=Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys | 31.3 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=993; Record_ID=skin_sensitization_invitro_272; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=31.3; Reported_Response_Unit=%; Response=31.3; Response_Unit=%; Reference=Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys | 37 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1005; Record_ID=skin_sensitization_invitro_275; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=37; Reported_Response_Unit=%; Response=37; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys | 75 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=997; Record_ID=skin_sensitization_invitro_273; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=75; Reported_Response_Unit=%; Response=75; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys + Cys | 19 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1007; Record_ID=skin_sensitization_invitro_275; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=19; Reported_Response_Unit=%; Response=19; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys + Cys | 24 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=995; Record_ID=skin_sensitization_invitro_272; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=24; Reported_Response_Unit=%; Response=24; Response_Unit=%; Reference=Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys + Cys | 37.5 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1003; Record_ID=skin_sensitization_invitro_274; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=37.5; Reported_Response_Unit=%; Response=37.5; Response_Unit=%; Reference=Jaworska 2011; 23670904; 10.1002/jat.2869; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Depletion Lys + Cys | 38.4 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=999; Record_ID=skin_sensitization_invitro_273; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=38.4; Reported_Response_Unit=%; Response=38.4; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | EC1.5 | 13.8 | uM | - | Dermal | - | In Vitro; KeratinoSens2015; KeratinoSens | sheet=Data_invitro; excel_row=6856; Record_ID=skin_sensitization_invitro_1622; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=13.8; Reported_Response_Unit=uM; Response=13.8; Response_Unit=uM; Reference=Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | EC1.5 | >2000 | uM | - | Dermal | - | In Vitro; KeratinoSens2015; KeratinoSens | sheet=Data_invitro; excel_row=6858; Record_ID=skin_sensitization_invitro_1623; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=KeratinoSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response=No induction; Reported_Response_Unit=Unitless; Conversion_Factor=Text to numeric; Conversion_Factor_Value=No induction assumed >2000 uM; Conversion_Factor_Source=Manually calculated; Converted_Response_Modifier=>; Converted_Response=2000; Converted_Response_Unit=uM; Response=2000; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | EC1.5 | >2400 | uM | - | Dermal | - | In Vitro; Urbisch_SkinSensitization2020; LuSens | sheet=Data_invitro; excel_row=7612; Record_ID=skin_sensitization_invitro_1854; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=LuSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=2400; Reported_Response_Unit=uM; Response=2400; Response_Unit=uM; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | EC3 | 0.16 | % | Mouse | Dermal | - | In Vivo; Urbisch_SkinSensitization2020; LLNA | sheet=Data_invivo; excel_row=12815; Record_ID=skin_sensitization_invivo_2813; Data_Type=In Vivo; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=LLNA; Endpoint=EC3; Response=0.16; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Imax | 0.3302 | ratio | - | Dermal | - | In Vitro; Urbisch_SkinSensitization2020; LuSens | sheet=Data_invitro; excel_row=7731; Record_ID=skin_sensitization_invitro_1854; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=LuSens; Endpoint=Imax; Reported_Response=0.330228588; Reported_Response_Unit=Unitless; Response=0.3302; Response_Unit=Ratio; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Imax | 1.3 | ratio | - | Dermal | - | In Vitro; KeratinoSens2015; KeratinoSens | sheet=Data_invitro; excel_row=6868; Record_ID=skin_sensitization_invitro_1623; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.3; Reported_Response_Unit=Unitless; Response=1.3; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
| NTP ICE skin sensitization | Imax | 1.54 | ratio | - | Dermal | - | In Vitro; KeratinoSens2015; KeratinoSens | sheet=Data_invitro; excel_row=6870; Record_ID=skin_sensitization_invitro_1622; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID2021159; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.54; Reported_Response_Unit=Unitless; Response=1.54; Response_Unit=Ratio; Reference=Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021159; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID2021159 |
EPA ToxRefDB v3 5 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| EPA ToxRefDB v3 | LEL | >750 | mg/kg bw/day | rat (fischer; Fischer 344) | oral | 0 day to 105 week | CHR | study_id=7494; toxval_study_source_id=studyid7494_Adult_F0_F_NA; dose_level=2; study_year=1979; study_citation=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Rat portion); dsstox_substance_id=DTXSID2021159; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5 |
| EPA ToxRefDB v3 | LEL | =1803 | mg/kg bw/day | mouse (b6c3f1; B6C3F1) | oral | 0 day to 104 week | CHR | study_id=7495; toxval_study_source_id=studyid7495_Adult_F0_F_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=1; study_year=1979; study_citation=NTP. BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Mouse portion); dsstox_substance_id=DTXSID2021159; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5 |
| EPA ToxRefDB v3 | LEL | =2452 | mg/kg bw/day | mouse (b6c3f1; B6C3F1) | oral | 0 day to 104 week | CHR | study_id=7495; toxval_study_source_id=studyid7495_Adult_F0_M_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=1; study_year=1979; study_citation=NTP. BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Mouse portion); dsstox_substance_id=DTXSID2021159; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5 |
| EPA ToxRefDB v3 | NEL | >0 | mg/kg bw/day | mouse (b6c3f1; B6C3F1) | oral | 0 day to 104 week | CHR | study_id=7495; toxval_study_source_id=studyid7495_Adult_F0_F_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=0; study_year=1979; study_citation=NTP. BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Mouse portion); dsstox_substance_id=DTXSID2021159; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5 |
| EPA ToxRefDB v3 | NEL | =375 | mg/kg bw/day | rat (fischer; Fischer 344) | oral | 0 day to 105 week | CHR | study_id=7494; toxval_study_source_id=studyid7494_Adult_F0_M_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=1; study_year=1979; study_citation=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Rat portion); dsstox_substance_id=DTXSID2021159; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5 |
ToxValDB Cal OEHHA REL derivations 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB Cal OEHHA REL derivations | LOAEL | =6.5 | mg/m3 | Human | inhalation | chronic; 13.3 years | occupational | LONG_REF=Nielsen J, Bensryd I, Almquist H, Dahlqvist M, Welinder H, Alexandersson R, and Skerfving S. 1991. Serum IgE and lung function in workers exposed to phthalic anhydride. Int. Arch. Occup. Environ. Health 63:199-204; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/68c97043e4b02565fc7d32ce; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://oehha.ca.gov/; SUBSOURCE_URL=https://oehha.ca.gov/sites/default/files/media/downloads/crnr/appendixd3final.pdf; YEAR=2000; ORIGINAL_YEAR=2000; TOXICOLOGICAL_EFFECT=Increased incidence of conjunctivitis, rhinitis, asthma, and chronic bronchitis; STUDY_GROUP=Cal OEHHA REL derivations:15952131:-:-occupationally-exposed workers; QC_CATEGORY=Manually extracted from unstructured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ab24a85d578c492c558955d79360847f |
ECHA 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ECHA | NOAEL | =1000 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab77e4b0a7c65d1ba745; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/10004/7/9/2?documentUUID=cdc5c29e-c6b2-4c01-a64b-dd89a2d80f86; YEAR=1968; ORIGINAL_YEAR=1968; STUDY_GROUP=ECHA IUCLID:15861435:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_3c803c7c152fbb889e44a77ac067228a |
| ECHA | NOAEL | =1785 | mg/kg bw/day | Mouse | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab77e4b0a7c65d1ba73f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/10004/7/9/2?documentUUID=cdc5c29e-c6b2-4c01-a64b-dd89a2d80f86; YEAR=1968; ORIGINAL_YEAR=1968; STUDY_GROUP=ECHA IUCLID:15861442:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_f7dfa9dd329ea024351982cd16f9dd6d |
| ECHA | NOAEL | =3570 | mg/kg bw/day | Mouse | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab77e4b0a7c65d1ba73f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/10004/7/9/2?documentUUID=cdc5c29e-c6b2-4c01-a64b-dd89a2d80f86; YEAR=1968; ORIGINAL_YEAR=1968; STUDY_GROUP=ECHA IUCLID:15861875:M:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_9163eee5589af45168f213508297abbd |
ToxValDB GESTIS DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB GESTIS DNEL | DNEL systemic | =49.4 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634180:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e03754c36a20fddcd27e704be3554d6b |
ToxValDB IRIS 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB IRIS | LOAEL | =1562 | mg/kg bw/day | Mouse | oral | chronic; 104 weeks | chronic | LONG_REF=NCI (National Cancer Institute). 1979. Bioassay of phthalic anhydride for possible carcinogenicity. NCI Carcinogenesis Tech. Rep. Ser. No. 159. NTIS PB293594.; TITLE=Bioassay of phthalic anhydride for possible carcinogenicity; AUTHOR=NCI (National Cancer Institute); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/652e8a3be4b045b9ff7a571e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.epa.gov/iris; SUBSOURCE_URL=https://iris.epa.gov/ChemicalLanding/&substance_nmbr=308; TOXICOLOGICAL_EFFECT=lung and kidney histopathology; TOXICOLOGICAL_EFFECT_CATEGORY=nonneoplastic histopathology; STUDY_GROUP=IRIS:15645534:F:--; QC_CATEGORY=Manually extracted from unstructured data source; Source overall passed QC, and this record was manually checked; QC_STATUS=pass; SOURCE_HASH=ToxValhc_e5e8d1ea0411d1ac236699c60168ea8e |
| ToxValDB IRIS | RfD | =2 | mg/kg bw/day | Human | oral | - | Toxicity Value | LONG_REF=NCI (National Cancer Institute). 1979. Bioassay of phthalic anhydride for possible carcinogenicity. NCI Carcinogenesis Tech. Rep. Ser. No. 159. NTIS PB293594.; TITLE=Bioassay of phthalic anhydride for possible carcinogenicity; AUTHOR=NCI (National Cancer Institute); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/652e8a3be4b045b9ff7a571e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.epa.gov/iris; SUBSOURCE_URL=https://iris.epa.gov/ChemicalLanding/&substance_nmbr=308; TOXICOLOGICAL_EFFECT=Lung and kidney histopathology in female mice; STUDY_GROUP=IRIS:15645299:-:--; QC_CATEGORY=Manually extracted from unstructured data source; Source overall passed QC, and this record was manually checked; QC_STATUS=pass; SOURCE_HASH=ToxValhc_0f369817359dec97af97a8b2b874b2d8 |
ToxValDB Pennsylvania DEP ToxValues 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB Pennsylvania DEP ToxValues | RfC | =0.02 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67599fbae4b0a7c65d37b2e3; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://files.dep.state.pa.us/EnvironmentalCleanupBrownfields/LandRecyclingProgram/LandRecyclingProgramPortalFiles/GuidanceTechTools/VaporIntrusion/November_2021/Table%205a.pdf; STUDY_GROUP=Pennsylvania DEP ToxValues:15650307:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_31359a942de5e1ad43cf2c924539c0c8 |
ToxValDB RSL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB RSL | RfC | =0.12 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759b87ce4b0a7c65d37b4e2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.epa.gov/risk/regional-screening-levels-rsls-generic-tables; STUDY_GROUP=RSL:15663725:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_97887847a65a5a3ed4c61a5aa6779849 |
ToxValDB ToxRefDB 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB ToxRefDB | LEL | >750 | mg/kg bw/day | Rat | oral | chronic; 105 weeks | chronic | LONG_REF=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Rat portion); TITLE=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9; AUTHOR=NCI; EXTERNAL_SOURCE_ID=7494; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1979; ORIGINAL_YEAR=1979; STUDY_GROUP=ToxRefDB_dup_-_15712755_15712756_15712757_15712758:F:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_122e5d9a8c6a99f0ac6c9f020440ea5e |
| ToxValDB ToxRefDB | LEL | =1803 | mg/kg bw/day | Mouse | oral | chronic; 104 weeks | chronic | LONG_REF=NTP. BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Mouse portion); TITLE=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9; AUTHOR=NTP; EXTERNAL_SOURCE_ID=7495; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1979; ORIGINAL_YEAR=1979; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ToxRefDB_dup_-_15712763_15712764:F:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2799aa03321755b421eed152617b5c14 |
| ToxValDB ToxRefDB | LEL | =2452 | mg/kg bw/day | Mouse | oral | chronic; 104 weeks | chronic | LONG_REF=NTP. BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Mouse portion); TITLE=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9; AUTHOR=NTP; EXTERNAL_SOURCE_ID=7495; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1979; ORIGINAL_YEAR=1979; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ToxRefDB_dup_-_15712765_15712766:M:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_8432bcd476b4e1f902ee57d9075a457f |
| ToxValDB ToxRefDB | NEL | =375 | mg/kg bw/day | Rat | oral | chronic; 105 weeks | chronic | LONG_REF=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9. Study No NCI-CG-TR-159. (Rat portion); TITLE=BIOASSAY OF PHTHALIC ANHYDRIDE FOR POSSIBLE CARCINOGENICITY, CAS No. 85-44-9; AUTHOR=NCI; EXTERNAL_SOURCE_ID=7494; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1979; ORIGINAL_YEAR=1979; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ToxRefDB_dup_-_15712759_15712760_15712761_15712762:M:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_3205bd76ee05be820afa4c3d9eded6c1 |
openFDA substances 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | UVL263I5BJ | UNII | - | - | - | chemical | - |