Phytosterol Esters

INCI: PHYTOSTEROL ESTERS

CAS Number
Multiple CAS numbers depending on the specific ester (e.g., Phytosteryl Isostearate, Phytosteryl Oleate, Phytosteryl Macadamiate). The generic "Phytosterol Esters" group does not carry one single CAS
Function
Skin conditioning, hair conditioning, emollient, viscosity increasing agent, skin protectant
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: Safe as used (Final Report, January 2014). Panel reviewed 26 phytosterol ingredients and concluded they are safe at current use concentrations (up to 8% in leave-on products)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No estrogenic activity in multiple in vitro and in vivo assays. Not genotoxic. Industry should control heavy metal impurities (Pb < 1 ppm, As < 1 ppm). Soy-derived variants: residual soy protein not detectable above ELISA limits but disclose soy origin for allergy labeling

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Concern Level: Low

Frequently Asked Questions

Is Phytosterol Esters safe in cosmetics?

No estrogenic activity in multiple in vitro and in vivo assays. Not genotoxic. Industry should control heavy metal impurities (Pb < 1 ppm, As < 1 ppm). Soy-derived variants: residual soy protein not detectable above ELISA limits but disclose soy origin for allergy labeling The EU classifies Phytosterol Esters as "permitted". Safety rating: EXCELLENT.

Is Phytosterol Esters allowed in the EU?

Phytosterol Esters EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phytosterol Esters do in cosmetics?

Phytosterol Esters functions as: Skin conditioning, hair conditioning, emollient, viscosity increasing agent, skin protectant. It is classified as a cosmetic ingredient in our database. CAS number: Multiple CAS numbers depending on the specific ester (e.g., Phytosteryl Isostearate, Phytosteryl Oleate, Phytosteryl Macadamiate). The generic "Phytosterol Esters" group does not carry one single CAS.

What is the Margin of Safety for Phytosterol Esters?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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