Moderate Cosmetic Ingredient

Piper Betle Leaf Powder

INCI: PIPER BETLE LEAF POWDER

CAS Number
Not specifically assigned (physical form of plant material)
Function
Humectant, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No FDA restriction; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Betel leaf is associated with oral carcinogenicity upon chronic chewing (WHO/IARC Group 1 carcinogen with tobacco); relevance to dermal cosmetic use unclear but must be addressed in CPSR narrative; no safrole risk assessment available for powder form

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Concern Level: Moderate

Frequently Asked Questions

Is Piper Betle Leaf Powder safe in cosmetics?

Betel leaf is associated with oral carcinogenicity upon chronic chewing (WHO/IARC Group 1 carcinogen with tobacco); relevance to dermal cosmetic use unclear but must be addressed in CPSR narrative; no safrole risk assessment available for powder form The EU classifies Piper Betle Leaf Powder as "permitted". Safety rating: MODERATE.

Is Piper Betle Leaf Powder allowed in the EU?

Piper Betle Leaf Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Piper Betle Leaf Powder do in cosmetics?

Piper Betle Leaf Powder functions as: Humectant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (physical form of plant material).

What is the Margin of Safety for Piper Betle Leaf Powder?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Piper Betle Leaf Powder compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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