Regulatory Status
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Safety Data
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Expert Verdict
Plumbago Rosea Root Extract contains plumbagin, which is cytotoxic, vesicant, and a documented abortifacient with organ toxicity potential. Root extracts can contain up to 80% w/w plumbagin in non-polar extracts, causing severe eye damage and sub-acute hepatic, adrenal, and cardiac toxicity. This ingredient requires extreme caution or avoidance in cosmetic products; if used, plumbagin content must be analytically controlled to ppb levels.
Regulatory Flags
Frequently Asked Questions
Is Plumbago Rosea Root Extract safe in cosmetics?
Plumbago Rosea Root Extract contains plumbagin, which is cytotoxic, vesicant, and a documented abortifacient with organ toxicity potential. Root extracts can contain up to 80% w/w plumbagin in non-polar extracts, causing severe eye damage and sub-acute hepatic, adrenal, and cardiac toxicity. This ingredient requires extreme caution or avoidance in cosmetic products; if used, plumbagin content must be analytically controlled to ppb levels. The EU classifies Plumbago Rosea Root Extract as "permitted". Safety rating: POOR.
Is Plumbago Rosea Root Extract allowed in the EU?
Plumbago Rosea Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Plumbago Rosea Root Extract do in cosmetics?
Plumbago Rosea Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not commonly assigned for the extract; plumbagin (active): CAS 481-42-5.
What is the Margin of Safety for Plumbago Rosea Root Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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