Plumbago Zeylanica Flower/Root Extract
INCI: PLUMBAGO ZEYLANICA FLOWER/ROOT EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
Contains plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) with cytotoxic activity toward cancer cell lines at low micromolar concentrations and moderate skin irritant potential (primary irritation index = 2.00 on rabbit model); root extract demonstrates higher toxicity than leaf or flower fractions.
Regulatory Flags
Frequently Asked Questions
Is Plumbago Zeylanica Flower/Root Extract safe in cosmetics?
Contains plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) with cytotoxic activity toward cancer cell lines at low micromolar concentrations and moderate skin irritant potential (primary irritation index = 2.00 on rabbit model); root extract demonstrates higher toxicity than leaf or flower fractions. The EU classifies Plumbago Zeylanica Flower/Root Extract as "permitted". Safety rating: MODERATE.
Is Plumbago Zeylanica Flower/Root Extract allowed in the EU?
Plumbago Zeylanica Flower/Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Plumbago Zeylanica Flower/Root Extract do in cosmetics?
Plumbago Zeylanica Flower/Root Extract functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 92202-07-8.
What is the Margin of Safety for Plumbago Zeylanica Flower/Root Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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