Poloxamer 184

INCI: POLOXAMER 184

CAS Number
9003-11-6 (generic for all Poloxamers)
Function
Cleansing, Emulsifying, Surfactant, Oral Care
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR assessed: safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Poloxamer 184 is permitted for use, but commercial grades may contain 1,4-dioxane and residual ethylene oxide/propylene oxide impurities; supplier purification specifications and batch testing are essential, and NY/CA 1,4-dioxane limits apply.

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Concern Level: Moderate

Frequently Asked Questions

Is Poloxamer 184 safe in cosmetics?

Poloxamer 184 is permitted for use, but commercial grades may contain 1,4-dioxane and residual ethylene oxide/propylene oxide impurities; supplier purification specifications and batch testing are essential, and NY/CA 1,4-dioxane limits apply. The EU classifies Poloxamer 184 as "permitted". Safety rating: GOOD.

Is Poloxamer 184 allowed in the EU?

Poloxamer 184 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamer 184 do in cosmetics?

Poloxamer 184 functions as: Cleansing, Emulsifying, Surfactant, Oral Care. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic for all Poloxamers).

What is the Margin of Safety for Poloxamer 184?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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