Poloxamer 282

INCI: POLOXAMER 282

CAS Number
9003-11-6 (generic)
Function
Surfactant – cleansing, surfactant – emulsifying
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR: safe as used (2008); FDA indirect food additive; no cosmetic-specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Trace residual ethylene oxide and propylene oxide possible; USP limits apply (EO ≤1 ppm, PO ≤5 ppm, 1,4-dioxane ≤5 ppm). Very limited cosmetic use history reported.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Poloxamer 282 safe in cosmetics?

Trace residual ethylene oxide and propylene oxide possible; USP limits apply (EO ≤1 ppm, PO ≤5 ppm, 1,4-dioxane ≤5 ppm). Very limited cosmetic use history reported. The EU classifies Poloxamer 282 as "permitted". Safety rating: GOOD.

Is Poloxamer 282 allowed in the EU?

Poloxamer 282 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamer 282 do in cosmetics?

Poloxamer 282 functions as: Surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic).

What is the Margin of Safety for Poloxamer 282?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Poloxamer 282 in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Poloxamer 282 in your formulation.