Poloxamer 284

INCI: POLOXAMER 284

CAS Number
9003-11-6 (generic)
Function
Surfactant – cleansing, surfactant – emulsifying
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR: safe as used (2008); FDA indirect food additive

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Trace 1,4-dioxane/EO/PO impurities present; minimal cosmetic use history reported in FDA VCRP.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Poloxamer 284 safe in cosmetics?

Trace 1,4-dioxane/EO/PO impurities present; minimal cosmetic use history reported in FDA VCRP. The EU classifies Poloxamer 284 as "permitted". Safety rating: GOOD.

Is Poloxamer 284 allowed in the EU?

Poloxamer 284 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamer 284 do in cosmetics?

Poloxamer 284 functions as: Surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic).

What is the Margin of Safety for Poloxamer 284?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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