Poloxamer 334

INCI: POLOXAMER 334

CAS Number
9003-11-6 (generic)
Function
Surfactant – cleansing, surfactant – emulsifying
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR: safe as used (2008); reported use at ≤0.3% in hair tonics (Pluronic P-104)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Poloxamer 334 is a permitted surfactant with adequate safety margin; trace 1,4-dioxane/EO/PO impurities possible but limited reported cosmetic use.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Poloxamer 334 safe in cosmetics?

Poloxamer 334 is a permitted surfactant with adequate safety margin; trace 1,4-dioxane/EO/PO impurities possible but limited reported cosmetic use. The EU classifies Poloxamer 334 as "permitted". Safety rating: GOOD.

Is Poloxamer 334 allowed in the EU?

Poloxamer 334 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamer 334 do in cosmetics?

Poloxamer 334 functions as: Surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic).

What is the Margin of Safety for Poloxamer 334?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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