Regulatory Status
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Safety Data
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Expert Verdict
Trace 1,4-dioxane/EO/PO impurities possible. Very low HLB makes this the most lipophilic in the series with potential to interact with skin lipid barrier at elevated concentrations.
Frequently Asked Questions
Is Poloxamer 401 safe in cosmetics?
Trace 1,4-dioxane/EO/PO impurities possible. Very low HLB makes this the most lipophilic in the series with potential to interact with skin lipid barrier at elevated concentrations. The EU classifies Poloxamer 401 as "permitted". Safety rating: GOOD.
Is Poloxamer 401 allowed in the EU?
Poloxamer 401 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Poloxamer 401 do in cosmetics?
Poloxamer 401 functions as: Surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic).
What is the Margin of Safety for Poloxamer 401?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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