Poloxamer 402

INCI: POLOXAMER 402

CAS Number
9003-11-6 (generic)
Function
Surfactant – cleansing, surfactant – emulsifying
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR: safe as used (2008); not reported in FDA VCRP

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Trace 1,4-dioxane/EO/PO impurities possible; minimal cosmetic use data available.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Poloxamer 402 safe in cosmetics?

Trace 1,4-dioxane/EO/PO impurities possible; minimal cosmetic use data available. The EU classifies Poloxamer 402 as "permitted". Safety rating: GOOD.

Is Poloxamer 402 allowed in the EU?

Poloxamer 402 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamer 402 do in cosmetics?

Poloxamer 402 functions as: Surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic).

What is the Margin of Safety for Poloxamer 402?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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