Good Cosmetic Ingredient

Polyglyceryl-10 Hexacaprylate/Caprate

INCI: POLYGLYCERYL-10 HEXACAPRYLATE/CAPRATE

CAS Number
Not individually assigned
Function
Surfactant – cleansing; skin conditioning; skin conditioning – emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR class reviewed (2023) — safe when formulated to be non-irritating; read-across from related polyglyceryl caprylate/caprate esters

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cleansing function indicates surfactant activity — may increase skin permeability at high concentrations; HET-CAM data on related caprylates showed moderate irritation at ≥4%

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Concern Level: Moderate

Frequently Asked Questions

Is Polyglyceryl-10 Hexacaprylate/Caprate safe in cosmetics?

Cleansing function indicates surfactant activity — may increase skin permeability at high concentrations; HET-CAM data on related caprylates showed moderate irritation at ≥4% The EU classifies Polyglyceryl-10 Hexacaprylate/Caprate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-10 Hexacaprylate/Caprate allowed in the EU?

Polyglyceryl-10 Hexacaprylate/Caprate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-10 Hexacaprylate/Caprate do in cosmetics?

Polyglyceryl-10 Hexacaprylate/Caprate functions as: Surfactant – cleansing; skin conditioning; skin conditioning – emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned.

What is the Margin of Safety for Polyglyceryl-10 Hexacaprylate/Caprate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Polyglyceryl-10 Hexacaprylate/Caprate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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