Polyglyceryl-10 Isostearate

INCI: POLYGLYCERYL-10 ISOSTEARATE

CAS Number
133738-23-5
Function
Skin conditioning agent – emollient; surfactant – emulsifying agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No FDA restriction; CIR 2023 — safe in present practices of use and concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Formulate to be non-irritating per CIR stipulation

⚠️
Concern Level: Low

Frequently Asked Questions

Is Polyglyceryl-10 Isostearate safe in cosmetics?

Formulate to be non-irritating per CIR stipulation The EU classifies Polyglyceryl-10 Isostearate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-10 Isostearate allowed in the EU?

Polyglyceryl-10 Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-10 Isostearate do in cosmetics?

Polyglyceryl-10 Isostearate functions as: Skin conditioning agent – emollient; surfactant – emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 133738-23-5.

What is the Margin of Safety for Polyglyceryl-10 Isostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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