Polyglyceryl-4 Diisostearate

INCI: POLYGLYCERYL-4 DIISOSTEARATE

CAS Number
85404-84-8 (tetraglycerol diisostearate)
Function
Skin conditioning agent, emollient, surfactant, emulsifier
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-reviewed: safe as part of polyglyceryl fatty acid esters group (2023)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe for use as part of polyglyceryl fatty acid esters; formulate to minimize irritation and monitor for glycidol and 3-MCPD residuals from glycerol polymerization.

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Concern Level: Low

Frequently Asked Questions

Is Polyglyceryl-4 Diisostearate safe in cosmetics?

Safe for use as part of polyglyceryl fatty acid esters; formulate to minimize irritation and monitor for glycidol and 3-MCPD residuals from glycerol polymerization. The EU classifies Polyglyceryl-4 Diisostearate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-4 Diisostearate allowed in the EU?

Polyglyceryl-4 Diisostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-4 Diisostearate do in cosmetics?

Polyglyceryl-4 Diisostearate functions as: Skin conditioning agent, emollient, surfactant, emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: 85404-84-8 (tetraglycerol diisostearate).

What is the Margin of Safety for Polyglyceryl-4 Diisostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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