Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Trisiloxane assessed as very persistent and very bioaccumulative; verify D4/D5/D6 cyclomethicone impurity levels must be less than 0.1% each for EU compliance; not covered by CIR polyglyceryl ester group; CPSR requires independent justification; environmental risk assessment may be needed for EU notification
Frequently Asked Questions
Is Polyglyceryl-4 Trisiloxane safe in cosmetics?
Trisiloxane assessed as very persistent and very bioaccumulative; verify D4/D5/D6 cyclomethicone impurity levels must be less than 0.1% each for EU compliance; not covered by CIR polyglyceryl ester group; CPSR requires independent justification; environmental risk assessment may be needed for EU notification The EU classifies Polyglyceryl-4 Trisiloxane as "permitted". Safety rating: MODERATE.
Is Polyglyceryl-4 Trisiloxane allowed in the EU?
Polyglyceryl-4 Trisiloxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglyceryl-4 Trisiloxane do in cosmetics?
Polyglyceryl-4 Trisiloxane functions as: Emulsifying agent (silicone-polyglyceryl hybrid emulsifier). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.
What is the Margin of Safety for Polyglyceryl-4 Trisiloxane?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Polyglyceryl-4 Trisiloxane compliance across multiple jurisdictions:
Related Ingredients
Is Polyglyceryl-4 Trisiloxane in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Polyglyceryl-4 Trisiloxane in your formulation.