Polyglyceryl-6 Diisostearate

INCI: POLYGLYCERYL-6 DIISOSTEARATE

CAS Number
Not specifically assigned (related: Polyglyceryl-10 Diisostearate = 102033-55-6 / 63705-03-3 generic)
Function
Emulsifier (W/O), emollient, viscosity controller
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; CIR group-reviewed โ€” safe when non-irritating. No individual VCRP use data or tox data in CIR matrix

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

W/O emulsifier with higher lipophilicity; ensure emulsion stability testing. Isostearic acid branching may affect skin penetration differently than straight-chain analogs.

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Concern Level: Low

Frequently Asked Questions

Is Polyglyceryl-6 Diisostearate safe in cosmetics?

W/O emulsifier with higher lipophilicity; ensure emulsion stability testing. Isostearic acid branching may affect skin penetration differently than straight-chain analogs. The EU classifies Polyglyceryl-6 Diisostearate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-6 Diisostearate allowed in the EU?

Polyglyceryl-6 Diisostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-6 Diisostearate do in cosmetics?

Polyglyceryl-6 Diisostearate functions as: Emulsifier (W/O), emollient, viscosity controller. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (related: Polyglyceryl-10 Diisostearate = 102033-55-6 / 63705-03-3 generic).

What is the Margin of Safety for Polyglyceryl-6 Diisostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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