Polygonum Bistorta Root Extract

INCI: POLYGONUM BISTORTA ROOT EXTRACT

CAS Number
84012-36-2
Function
Skin conditioning; anti-aging (inhibits hyaluronidase, collagenase, elastase); antioxidant (32% oxidative stress reduction in vitro)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; permitted under general cosmetic provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High tannin content produces astringent effects at elevated levels with potential for mild contact irritation in compromised skin; no phototoxicity data available.

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Polygonum Bistorta Root Extract safe in cosmetics?

High tannin content produces astringent effects at elevated levels with potential for mild contact irritation in compromised skin; no phototoxicity data available. The EU classifies Polygonum Bistorta Root Extract as "permitted". Safety rating: GOOD.

Is Polygonum Bistorta Root Extract allowed in the EU?

Polygonum Bistorta Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polygonum Bistorta Root Extract do in cosmetics?

Polygonum Bistorta Root Extract functions as: Skin conditioning; anti-aging (inhibits hyaluronidase, collagenase, elastase); antioxidant (32% oxidative stress reduction in vitro). It is classified as a cosmetic ingredient in our database. CAS number: 84012-36-2.

What is the Margin of Safety for Polygonum Bistorta Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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