Poor Cosmetic Ingredient

Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate

INCI: POLYPERFLUOROETHOXYMETHOXY DIFLUOROETHYL PEG DIISOSTEARATE

CAS Number
Not publicly listed in standard databases
Function
Skin conditioning; emollient (PFAS-PEG-fatty acid hybrid)
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status restricted
US Notes Not specifically restricted at federal level currently, but subject to increasing US state-level PFAS bans in cosmetics (CA, WA, CO, MN)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS forever chemical with environmental persistence and bioaccumulative potential. Subject to upcoming EU universal PFAS ban and already banned in cosmetics in several US states. Incompatible with COSMOS/ECOCERT standards. Significant reputational liability.

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Concern Level: High

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate safe in cosmetics?

PFAS forever chemical with environmental persistence and bioaccumulative potential. Subject to upcoming EU universal PFAS ban and already banned in cosmetics in several US states. Incompatible with COSMOS/ECOCERT standards. Significant reputational liability. The EU classifies Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate as "restricted". Safety rating: POOR.

Is Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate allowed in the EU?

Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate do in cosmetics?

Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate functions as: Skin conditioning; emollient (PFAS-PEG-fatty acid hybrid). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in standard databases.

What is the Margin of Safety for Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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