Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether

INCI: POLYPERFLUOROETHOXYMETHOXY DIFLUOROHYDROXYETHYL ETHER

CAS Number
88645-29-8
Function
Skin conditioning; emollient
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted federally; affected by state PFAS cosmetic bans

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS compound with persistent and bioaccumulative concerns. Hydroxyl group increases polarity but does not mitigate environmental persistence of perfluorinated chain. Regulatory phase-out imminent in EU.

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Concern Level: High

Frequently Asked Questions

Is Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether safe in cosmetics?

PFAS compound with persistent and bioaccumulative concerns. Hydroxyl group increases polarity but does not mitigate environmental persistence of perfluorinated chain. Regulatory phase-out imminent in EU. The EU classifies Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether as "permitted". Safety rating: POOR.

Is Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether allowed in the EU?

Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether do in cosmetics?

Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether functions as: Skin conditioning; emollient. It is classified as a cosmetic ingredient in our database. CAS number: 88645-29-8.

What is the Margin of Safety for Polyperfluoroethoxymethoxy Difluorohydroxyethyl Ether?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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