Good Cosmetic Ingredient SCCS/CIR Reviewed

Polyquaternium-4 (HEC/DMDAAC Copolymer)

INCI: POLYQUATERNIUM-4

CAS Number
55963-33-2
Function
Antistatic, film forming, hair conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no FDA restriction; CIR has reviewed polyquaternium class ingredients

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe

ailable data and concluded that these ingredients are safe in cosmetics in the present practices of use and concentrations described in this safety assessment. Keywords Safety, Cosmetics, Cosmetic Ingredient Review, Expert Panel for Cosmetic Ingredient Safety, Distarch Phosphate, Distarch Phosph

Expert Verdict

Cationic polymer with potential for eye irritation; monomer residuals (DMDAAC) should be controlled; rinse-off applications recommended for sensitive populations.

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Concern Level: Low

Frequently Asked Questions

Is Polyquaternium-4 (HEC/DMDAAC Copolymer) safe in cosmetics?

Cationic polymer with potential for eye irritation; monomer residuals (DMDAAC) should be controlled; rinse-off applications recommended for sensitive populations. The EU classifies Polyquaternium-4 (HEC/DMDAAC Copolymer) as "permitted". Safety rating: GOOD. This ingredient has been reviewed by cir.

Is Polyquaternium-4 (HEC/DMDAAC Copolymer) allowed in the EU?

Polyquaternium-4 (HEC/DMDAAC Copolymer) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyquaternium-4 (HEC/DMDAAC Copolymer) do in cosmetics?

Polyquaternium-4 (HEC/DMDAAC Copolymer) functions as: Antistatic, film forming, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 55963-33-2.

What is the Margin of Safety for Polyquaternium-4 (HEC/DMDAAC Copolymer)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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