Polyquaternium-43

INCI: POLYQUATERNIUM-43

CAS Number
Not confirmed from available sources
Function
Antistatic, Film Forming, Hair Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; not CIR-reviewed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains acrylamide monomer with residual content requiring tight control. DMAPA (dimethylaminopropylamine) is a known sensitizer; residual DMAPA must be verified at <100 ppm. No dedicated safety assessment exists.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Polyquaternium-43 safe in cosmetics?

Contains acrylamide monomer with residual content requiring tight control. DMAPA (dimethylaminopropylamine) is a known sensitizer; residual DMAPA must be verified at <100 ppm. No dedicated safety assessment exists. The EU classifies Polyquaternium-43 as "permitted". Safety rating: MODERATE.

Is Polyquaternium-43 allowed in the EU?

Polyquaternium-43 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyquaternium-43 do in cosmetics?

Polyquaternium-43 functions as: Antistatic, Film Forming, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from available sources.

What is the Margin of Safety for Polyquaternium-43?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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