Populus Nigra Bud Extract

INCI: POPULUS NIGRA BUD EXTRACT

CAS Number
84650-39-5
Function
Skin conditioning; anti-inflammatory (salicin content)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High sensitization risk with documented cross-reactivity to propolis, balsam of Peru, and Myroxylon pereirae; anti-inflammatory claims may trigger drug classification scrutiny due to salicin content.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Populus Nigra Bud Extract safe in cosmetics?

High sensitization risk with documented cross-reactivity to propolis, balsam of Peru, and Myroxylon pereirae; anti-inflammatory claims may trigger drug classification scrutiny due to salicin content. The EU classifies Populus Nigra Bud Extract as "permitted". Safety rating: MODERATE.

Is Populus Nigra Bud Extract allowed in the EU?

Populus Nigra Bud Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Populus Nigra Bud Extract do in cosmetics?

Populus Nigra Bud Extract functions as: Skin conditioning; anti-inflammatory (salicin content). It is classified as a cosmetic ingredient in our database. CAS number: 84650-39-5.

What is the Margin of Safety for Populus Nigra Bud Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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