Good Cosmetic Ingredient NOAEL Data

Potassium Lauryl Phosphate

INCI: POTASSIUM LAURYL PHOSPHATE

CAS Number
39322-78-6
Function
Surfactant – Cleansing
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted; CIR has assessed alkyl phosphates — safe at reported use concentrations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Potassium Lauryl Phosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 600 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 500 mg/kg bw/day oral rat oral REACH

Expert Verdict

Anionic surfactant with good safety profile; potential for irritation at high concentrations in leave-on products but no identified risk impurities at approved use levels.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Potassium Lauryl Phosphate safe in cosmetics?

Anionic surfactant with good safety profile; potential for irritation at high concentrations in leave-on products but no identified risk impurities at approved use levels. The EU classifies Potassium Lauryl Phosphate as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is Potassium Lauryl Phosphate allowed in the EU?

Potassium Lauryl Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Potassium Lauryl Phosphate do in cosmetics?

Potassium Lauryl Phosphate functions as: Surfactant – Cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 39322-78-6.

What is the Margin of Safety for Potassium Lauryl Phosphate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Potassium Lauryl Phosphate?

The NOAEL (No Observed Adverse Effect Level) for Potassium Lauryl Phosphate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

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