Potassium PCA

INCI: POTASSIUM PCA

CAS Number
4810-50-8
Function
Skin conditioning agent — humectant (Natural Moisturizing Factor component)
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted; CIR Expert Panel confirmed safe in present practices of use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted for use; however, avoid combining with nitrosating preservatives or raw materials due to PCA being a secondary amine precursor that can react with nitrosating agents to form N-nitroso compounds.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Potassium PCA safe in cosmetics?

Permitted for use; however, avoid combining with nitrosating preservatives or raw materials due to PCA being a secondary amine precursor that can react with nitrosating agents to form N-nitroso compounds. The EU classifies Potassium PCA as "permitted". Safety rating: EXCELLENT.

Is Potassium PCA allowed in the EU?

Potassium PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Potassium PCA do in cosmetics?

Potassium PCA functions as: Skin conditioning agent — humectant (Natural Moisturizing Factor component). It is classified as a cosmetic ingredient in our database. CAS number: 4810-50-8.

What is the Margin of Safety for Potassium PCA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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