Good Cosmetic Ingredient NOAEL Data

Potassium Silicate

INCI: POTASSIUM SILICATE

CAS Number
1312-76-1
Function
Anticorrosive, buffering (pH control)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; CIR concluded safe when formulated to avoid irritation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

7 study endpoints found for Potassium Silicate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >227 mg/kg bw/day oral rat oral REACH
NOAEL 260 mg/kg bw/day oral mouse oral REACH
NOAEL >159 mg/kg bw/day oral rat oral REACH
NOAEL >159 mg/kg bw/day oral rat oral REACH
NOAEL >227 mg/kg bw/day oral rat oral REACH
NOAEL 260 mg/kg bw/day oral mouse oral REACH
NOAEL >227 mg/kg bw/day oral - oral REACH

Expert Verdict

Strongly alkaline with significant irritation potential in leave-on products; requires pH control and irritation-mitigation formulation; CIR conditional safety conclusion

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Concern Level: Moderate

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is Potassium Silicate safe in cosmetics?

Strongly alkaline with significant irritation potential in leave-on products; requires pH control and irritation-mitigation formulation; CIR conditional safety conclusion The EU classifies Potassium Silicate as "permitted". Safety rating: GOOD. 7 toxicological study endpoint(s) are available in our database.

Is Potassium Silicate allowed in the EU?

Potassium Silicate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Potassium Silicate do in cosmetics?

Potassium Silicate functions as: Anticorrosive, buffering (pH control). It is classified as a cosmetic ingredient in our database. CAS number: 1312-76-1.

What is the Margin of Safety for Potassium Silicate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Potassium Silicate?

The NOAEL (No Observed Adverse Effect Level) for Potassium Silicate is >227 mg/kg bw/day based on a oral study via oral route in rat. A total of 7 study endpoints are available. Source: REACH.

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