NOAEL Studies Cosmetic Ingredient

Potassium Taurate NOAEL Studies

INCI: POTASSIUM TAURATE

CAS: PubChem CID 23698856; molecular formula C₂H₆KNO₃S (CAS not widely catalogued — confirm with supplier CoA)

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

CIR Safety Assessment 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
CIR Safety Assessment NOAEL =1000 mg/kg/d rat oral 14-day repeated dose toxicity {"citation":"14; 28; 7)","dose":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0....","effect":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0.662 g/kg sodium methyl oleoyl taurate was administered by gavage 6 days/week for 25 doses to 10 mice, 1 mouse was dead on day 5 and 5 were dead on day 10 due to the test substance. No additional mice died through day 25.45 Inhalation No published repeated dose inhalation toxicity studies were found in the published literature and no unpublis","page":6,"pdf":"FR702.pdf","row_type":"noael_study","study_id":"FR702_noael_001"}
CIR Safety Assessment NOAEL =1000 mg/kg/d rat oral 14-day repeated dose toxicity {"citation":"14; 28; 7)","dose":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0....","effect":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0.662 g/kg sodium methyl oleoyl taurate was administered by gavage 6 days/week for 25 doses to 10 mice, 1 mouse was dead on day 5 and 5 were dead on day 10 due to the test substance. No additional mice died through day 25.45 Inhalation No published repeated dose inhalation toxicity studies were found in the published literature and no unpublis","page":6,"pdf":"FR702.pdf","row_type":"noael_study","study_id":"FR702_noael_001"}
CIR Safety Assessment NOAEL =1000 mg/kg/d rat oral 14-day repeated dose toxicity {"citation":"14; 28; 7)","dose":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0....","effect":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0.662 g/kg sodium methyl oleoyl taurate was administered by gavage 6 days/week for 25 doses to 10 mice, 1 mouse was dead on day 5 and 5 were dead on day 10 due to the test substance. No additional mice died through day 25.45 Inhalation No published repeated dose inhalation toxicity studies were found in the published literature and no unpublis","page":6,"pdf":"FR702.pdf","row_type":"noael_study","study_id":"FR702_noael_001"}
CIR Safety Assessment NOAEL =1000 mg/kg/d rat oral 14-day repeated dose toxicity {"citation":"14; 28; 7)","dose":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0....","effect":"Oral – Non-Human The no-observed-adverse-effects-level (NOAEL) was reported to be ≥1000 mg/kg/d for both sodium methyl cocoyl taurate and sodium methyl oleoyl taurate in 14-day oral toxicity studies in rats; there were no clinical signs in a 28-day oral toxicity study of sodium methyl cocoyl taurate in rats at up to 1000 mg/kg/d (Table 7).12,13,18 When 0.662 g/kg sodium methyl oleoyl taurate was administered by gavage 6 days/week for 25 doses to 10 mice, 1 mouse was dead on day 5 and 5 were dead on day 10 due to the test substance. No additional mice died through day 25.45 Inhalation No published repeated dose inhalation toxicity studies were found in the published literature and no unpublis","page":6,"pdf":"FR702.pdf","row_type":"noael_study","study_id":"FR702_noael_001"}