PPG-16

CAS Number
25322-69-4 (polypropylene glycol family)
Function
Skin conditioning, solvent, viscosity decreasing agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; CIR concluded PPGs are safe at concentrations up to 50%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PPG-16 is permitted in both EU and US; verify propylene oxide impurity content below USP limits and conduct patch testing for leave-on products above 10% concentration due to potential skin irritation at high levels.

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Concern Level: Low

Frequently Asked Questions

Is PPG-16 safe in cosmetics?

PPG-16 is permitted in both EU and US; verify propylene oxide impurity content below USP limits and conduct patch testing for leave-on products above 10% concentration due to potential skin irritation at high levels. The EU classifies PPG-16 as "permitted". Safety rating: GOOD.

Is PPG-16 allowed in the EU?

PPG-16 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PPG-16 do in cosmetics?

PPG-16 functions as: Skin conditioning, solvent, viscosity decreasing agent. It is classified as a cosmetic ingredient in our database. CAS number: 25322-69-4 (polypropylene glycol family).

What is the Margin of Safety for PPG-16?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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