NOAEL Studies Cosmetic Ingredient

PPG-3 Glyceryl Ether Triacrylate NOAEL Studies

INCI: PPG-3 GLYCERYL ETHER TRIACRYLATE

CAS: 52408-84-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 6 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID LOAEL =1000 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac32e4b0a7c65d1bddd7; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14734?documentUUID=47e58d75-d068-484e-99bd-8bb01af826c6; YEAR=2007; ORIGINAL_YEAR=2007; TOXICOLOGICAL_EFFECT=maternal: body weight and weight gain; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15824876_15824877:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_71a7074c3c3a0d362a42e2ae5c120ca9
ToxValDB_ECHA_IUCLID LOAEL =500 mg/kg bw/day Rabbit dermal short-term; 14 days short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61d93e4b096bca877647f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14734?documentUUID=47e58d75-d068-484e-99bd-8bb01af826c6; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID:15826220:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_075b1edaa1ba19cfd0bb22221a0cc069
ToxValDB_ECHA_IUCLID NOAEL >1000 mg/kg bw/day Rat oral - developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac32e4b0a7c65d1bddd7; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14734?documentUUID=47e58d75-d068-484e-99bd-8bb01af826c6; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15824878_15824879:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_321bb9ab89fe5615741cf74565e521bf
ToxValDB_ECHA_IUCLID NOAEL =150 mg/kg bw/day Rat oral subchronic (developmental); 58 days reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae5ae4b0a7c65d1c8d0a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14734?documentUUID=47e58d75-d068-484e-99bd-8bb01af826c6; YEAR=2007; ORIGINAL_YEAR=2007; TOXICOLOGICAL_EFFECT=histopathology: nonneoplastic; TOXICOLOGICAL_EFFECT_CATEGORY=nonneoplastic histopathology; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15838278_15841968_15847924_15848761:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ff0288933a0f43134327e2e1ffc02c8c
ToxValDB_ECHA_IUCLID NOAEL =375 mg/kg bw/day Rat oral subchronic (developmental); 58 days reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae5ae4b0a7c65d1c8c80; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14241?documentUUID=25f67530-d75f-4111-af18-c8a80e74820d; YEAR=2001; ORIGINAL_YEAR=2001; TOXICOLOGICAL_EFFECT=mortality; TOXICOLOGICAL_EFFECT_CATEGORY=mortality/survival; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15838278_15841968_15847924_15848761:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_7aec48e30585d3a1c3f00591d3191e87
ToxValDB_ECHA_IUCLID NOAEL =750 mg/kg bw/day Rat oral - developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab0ce4b0a7c65d1b88c6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14734?documentUUID=47e58d75-d068-484e-99bd-8bb01af826c6; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID:15861180:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_d3240580804d27a03a3f64d1e2601ffb
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =7.4 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634220:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_af922f78b2f9ef5f25ba8442c090b3c9
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier NQ23FMS7BT UNII - - - chemical {"approval_status":null,"molecular_formula":"C21H32O9","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NQ23FMS7BT"}
openFDA substances FDA UNII substance identifier NQ23FMS7BT UNII - - - chemical {"approval_status":null,"molecular_formula":"C21H32O9","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NQ23FMS7BT"}
openFDA substances FDA UNII substance identifier NQ23FMS7BT UNII - - - chemical {"approval_status":null,"molecular_formula":"C21H32O9","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NQ23FMS7BT"}
openFDA substances FDA UNII substance identifier NQ23FMS7BT UNII - - - chemical {"approval_status":null,"molecular_formula":"C21H32O9","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NQ23FMS7BT"}