Prolyl Histamine HCl
INCI: PROLYL HISTAMINE HCL (PROPRIETARY/PROPOSED INCI)
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
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Expert Verdict
Histamine component raises concerns for vasodilation, erythema, irritation, and pseudo-allergic reactions. Requires robust safety dossier before use. Not widely adopted.
Frequently Asked Questions
Is Prolyl Histamine HCl safe in cosmetics?
Histamine component raises concerns for vasodilation, erythema, irritation, and pseudo-allergic reactions. Requires robust safety dossier before use. Not widely adopted. The EU classifies Prolyl Histamine HCl as "permitted". Safety rating: MODERATE.
Is Prolyl Histamine HCl allowed in the EU?
Prolyl Histamine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Prolyl Histamine HCl do in cosmetics?
Prolyl Histamine HCl functions as: Skin conditioning (dipeptide derivative). It is classified as a cosmetic ingredient in our database. CAS number: No publicly assigned CAS in major cosmetic databases.
What is the Margin of Safety for Prolyl Histamine HCl?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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