Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Propylene Glycol Caprylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Safe emollient ester with confirmed penetration enhancement activity requiring careful co-formulation considerations when used with actives relying on low dermal absorption.
Regulatory Flags
Frequently Asked Questions
Is Propylene Glycol Caprylate safe in cosmetics?
Safe emollient ester with confirmed penetration enhancement activity requiring careful co-formulation considerations when used with actives relying on low dermal absorption. The EU classifies Propylene Glycol Caprylate as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Propylene Glycol Caprylate allowed in the EU?
Propylene Glycol Caprylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Propylene Glycol Caprylate do in cosmetics?
Propylene Glycol Caprylate functions as: Emollient, surfactant, penetration enhancer, solubilizer. It is classified as a cosmetic ingredient in our database. CAS number: 31565-12-5.
What is the Margin of Safety for Propylene Glycol Caprylate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Propylene Glycol Caprylate?
The NOAEL (No Observed Adverse Effect Level) for Propylene Glycol Caprylate is >=1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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