Propylene Glycol Diisostearate

INCI: PROPYLENE GLYCOL DIISOSTEARATE

CAS Number
68958-54-3
Function
Skin-conditioning agent (occlusive); viscosity increasing agent (nonaqueous)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR safe as used (1999); reaffirmed in 2014 group assessment

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited direct toxicity data; safety by read-across; production method not identified in published literature

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Concern Level: Moderate

Frequently Asked Questions

Is Propylene Glycol Diisostearate safe in cosmetics?

Limited direct toxicity data; safety by read-across; production method not identified in published literature The EU classifies Propylene Glycol Diisostearate as "permitted". Safety rating: GOOD.

Is Propylene Glycol Diisostearate allowed in the EU?

Propylene Glycol Diisostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Diisostearate do in cosmetics?

Propylene Glycol Diisostearate functions as: Skin-conditioning agent (occlusive); viscosity increasing agent (nonaqueous). It is classified as a cosmetic ingredient in our database. CAS number: 68958-54-3.

What is the Margin of Safety for Propylene Glycol Diisostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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