Propylene Glycol Dioleate

INCI: PROPYLENE GLYCOL DIOLEATE

CAS Number
105-62-4
Function
Skin-conditioning agent (occlusive); viscosity increasing agent (nonaqueous)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR safe as used (1999, reaffirmed 2014)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Notable penetration enhancer โ€” demonstrated 2.11ร— enhancement of lidocaine; use caution with actives whose safety depends on limited absorption

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Concern Level: Low

Frequently Asked Questions

Is Propylene Glycol Dioleate safe in cosmetics?

Notable penetration enhancer โ€” demonstrated 2.11ร— enhancement of lidocaine; use caution with actives whose safety depends on limited absorption The EU classifies Propylene Glycol Dioleate as "permitted". Safety rating: GOOD.

Is Propylene Glycol Dioleate allowed in the EU?

Propylene Glycol Dioleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Dioleate do in cosmetics?

Propylene Glycol Dioleate functions as: Skin-conditioning agent (occlusive); viscosity increasing agent (nonaqueous). It is classified as a cosmetic ingredient in our database. CAS number: 105-62-4.

What is the Margin of Safety for Propylene Glycol Dioleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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