Pyridoxine Hydroxybenzoate

INCI: PYRIDOXINE HYDROXYBENZOATE

CAS Number
Not widely published; listed in CosIng without a primary CAS
Function
Skin conditioning (pyridoxine ester with hydroxybenzoic acid — combines B6 activity with paraben-related moiety)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted in cosmetics under general provisions; no specific FDA monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

The hydroxybenzoate moiety will hydrolyse to release p-hydroxybenzoic acid — formulators should evaluate whether this triggers paraben-related regulatory scrutiny in target markets (EU paraben restrictions in Annex V apply to parabens themselves, not necessarily this ester, but safety assessors may flag it)

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Pyridoxine Hydroxybenzoate safe in cosmetics?

The hydroxybenzoate moiety will hydrolyse to release p-hydroxybenzoic acid — formulators should evaluate whether this triggers paraben-related regulatory scrutiny in target markets (EU paraben restrictions in Annex V apply to parabens themselves, not necessarily this ester, but safety assessors may flag it) The EU classifies Pyridoxine Hydroxybenzoate as "permitted". Safety rating: MODERATE.

Is Pyridoxine Hydroxybenzoate allowed in the EU?

Pyridoxine Hydroxybenzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyridoxine Hydroxybenzoate do in cosmetics?

Pyridoxine Hydroxybenzoate functions as: Skin conditioning (pyridoxine ester with hydroxybenzoic acid — combines B6 activity with paraben-related moiety). It is classified as a cosmetic ingredient in our database. CAS number: Not widely published; listed in CosIng without a primary CAS.

What is the Margin of Safety for Pyridoxine Hydroxybenzoate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Pyridoxine Hydroxybenzoate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Pyridoxine Hydroxybenzoate in your formulation.