Regulatory Status
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Safety Data
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Expert Verdict
Nitrone spin-trap chemistry — while the mechanism (trapping free radicals) is beneficial, the resulting radical adducts should be considered in the safety assessment. Less commercially established than PBN. Ensure supplier provides genotoxicity/mutagenicity data, as nitrone derivatives warrant this screening [^1_17][^1_18]
Frequently Asked Questions
Is Pyridyloxide T-Butylnitrone safe in cosmetics?
Nitrone spin-trap chemistry — while the mechanism (trapping free radicals) is beneficial, the resulting radical adducts should be considered in the safety assessment. Less commercially established than PBN. Ensure supplier provides genotoxicity/mutagenicity data, as nitrone derivatives warrant this screening [^1_17][^1_18] The EU classifies Pyridyloxide T-Butylnitrone as "permitted". Safety rating: MODERATE.
Is Pyridyloxide T-Butylnitrone allowed in the EU?
Pyridyloxide T-Butylnitrone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pyridyloxide T-Butylnitrone do in cosmetics?
Pyridyloxide T-Butylnitrone functions as: Antioxidant (radical spin-trap agent); structurally analogous to PBN (Phenyl T-Butylnitrone) but with a pyridine N-oxide ring for enhanced radical scavenging [^1_18][^1_17]. It is classified as a cosmetic ingredient in our database. CAS number: 66893-81-0 [^1_17].
What is the Margin of Safety for Pyridyloxide T-Butylnitrone?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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