Is QUILLAJA SAPONARIA BARK EXTRACT safe in cosmetics?
QUILLAJA SAPONARIA BARK EXTRACT has a safety rating of "GOOD" in our database. EU status: permitted. 3 toxicological study endpoint(s) are available in our database.
QUILLAJA SAPONARIA BARK EXTRACT
Also known as: EINECS 273-620-4, Quillaja saponaria pollen
QUILLAJA SAPONARIA BARK EXTRACT (CAS 68990-67-0) is a cosmetic cosmetic ingredient functioning as Anti-seborrheic, Cleansing, Foaming, Fragrance, Moisturising, Skin. NOAEL 1500 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68990-67-0 →
Auto-generated CPSR Part A draft with source citations
Function
Anti-seborrheic, Cleansing, Foaming, Fragrance, Moisturising, Skin Conditioning, Surfactant - Cleansing, Surfactant - Emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
3 study endpoints found for QUILLAJA SAPONARIA BARK EXTRACT. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1175 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1180 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 2200 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for QUILLAJA SAPONARIA BARK EXTRACT across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-dandruff
Cleaning agent
Deodorizer
Emulsifier
Flavouring and nutrient
Foamant
Fragrance
Humectant
Softener and conditioner
Surfactant (surface active agent)
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for QUILLAJA SAPONARIA BARK EXTRACT.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
fragrance
surfactant
needs-enrichment
ifra_fragrance
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to QUILLAJA SAPONARIA BARK EXTRACT by CAS number or substance name.
Studies
3
Lowest NOAEL
1175 mg/kg bw/day
Highest NOAEL
2200 mg/kg bw/day
COSMOS_DB
Known Synonyms
EINECS 273-620-4
Quillaja saponaria pollen
Chemical Function
Fragrance
Surfactant (surface active agent)
Deodorizer
Softener and conditioner
Emulsifier
Cleaning agent
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is QUILLAJA SAPONARIA BARK EXTRACT allowed in the EU?
QUILLAJA SAPONARIA BARK EXTRACT EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does QUILLAJA SAPONARIA BARK EXTRACT do in cosmetics?
QUILLAJA SAPONARIA BARK EXTRACT functions as: Anti-seborrheic, Cleansing, Foaming, Fragrance, Moisturising, Skin Conditioning, Surfactant - Cleansing, Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 68990-67-0.
What is the NOAEL for QUILLAJA SAPONARIA BARK EXTRACT?
The NOAEL (No Observed Adverse Effect Level) for QUILLAJA SAPONARIA BARK EXTRACT is 1175 mg/kg bw/day based on a Carcinogenicity study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Is QUILLAJA SAPONARIA BARK EXTRACT used outside cosmetics?
QUILLAJA SAPONARIA BARK EXTRACT also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check QUILLAJA SAPONARIA BARK EXTRACT compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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