QUILLAJA SAPONARIA BARK EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
5 study endpoints found for QUILLAJA SAPONARIA BARK EXTRACT. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 25 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2200 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 1180 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1175 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| dose_tested | 25 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
QUILLAJA SAPONARIA BARK EXTRACT is listed in the EU CosIng database with functions: Anti-seborrheic, Cleansing, Foaming, Fragrance, Moisturising, Skin Conditioning, Surfactant - Cleansing, Surfactant - Emulsifying It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is QUILLAJA SAPONARIA BARK EXTRACT safe in cosmetics?
QUILLAJA SAPONARIA BARK EXTRACT is listed in the EU CosIng database with functions: Anti-seborrheic, Cleansing, Foaming, Fragrance, Moisturising, Skin Conditioning, Surfactant - Cleansing, Surfactant - Emulsifying It is permitted in the EU without specific restrictions. The EU classifies QUILLAJA SAPONARIA BARK EXTRACT as "Permitted". Safety rating: GOOD. 5 toxicological study endpoint(s) are available in our database.
Is QUILLAJA SAPONARIA BARK EXTRACT allowed in the EU?
QUILLAJA SAPONARIA BARK EXTRACT EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does QUILLAJA SAPONARIA BARK EXTRACT do in cosmetics?
QUILLAJA SAPONARIA BARK EXTRACT functions as: Anti-seborrheic, Cleansing, Foaming, Fragrance, Moisturising, Skin Conditioning, Surfactant - Cleansing, Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 68990-67-0.
What is the NOAEL for QUILLAJA SAPONARIA BARK EXTRACT?
The NOAEL (No Observed Adverse Effect Level) for QUILLAJA SAPONARIA BARK EXTRACT is 25 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 5 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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